When running on Linux, the best is to run the Linux applications natively. Running Windows applications through Wine sometimes does not get the results you might have expected. I tried Notepad++ through Wine, a lot of features were missed from the program. At the end, I chose to use Gedit, Bluefish or Screem to edit html files.
See also:
Best Free Software for Linux (more good software will be added to the list when we move forward)
Tips and Tricks for Ubuntu after Installation