Anti-Virus Comparatives is one of the world's most respected testers of antivirus software. They publish details of their evaluations on a regular basis, which go into great detail about how the leading products performed when spotting malware and producing false positives.
If you're thinking about changing your antivirus product, look no further than http://www.av-comparatives.org/detection-test/ for the latest report. It's a great place to start drawing up your short list of candidates, before perhaps trying 2 or 3 different products to see which one you actually prefer to use.
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