A powerful, time-proven program with a well thought out user interface.
Pros & Cons:
FeedDemon is a powerful, time-proven program with a well thought out user interface. It can be intimidating to new RSS users, but most are able to learn to use FeedDemon fairly quickly, and it has an excellent help facility. The develoment of FeedDemon has been discontinued, but it is still downloadable from the official website and will continue to work without Google Reader synchronization.
You can subscribe to audio podcasts and play them directly from FeedDemon as well. FeedDemon also handles secure feeds (those that require a username and password). You may still be able to create a portable version of FeedDemon.
Update: Nick Bradbury has released a last, free version of FeedDemon Pro, which no longer links to Google Reader.
"FeedDemon requires Windows XP, Windows Vista or Windows 7, with Internet Explorer 7 or later installed." It's been running fine for me on Windows 8 as well.
FeedDemon was reviewed by Gizmos Freeware on based on version 4.5.